New kit makes classroom CRISPR experiments affordable and accessible
CRISPR, the gene-editing technology, has been one of the major breakthroughs in biology in the last two decades. And while ...
The EMBO Journal6d
Glutaminolysis provides nucleotides and amino acids to regulate osteoclast differentiation in mice
Metabolic rewiring is essential for osteoclast differentiation and bone resorption. This study shows that glutaminolysis ...
The EMBO Journal22h
Liver protects neuron viability and electrocortical activity in post-cardiac arrest brain injury
The liver function in post-cardiac arrest brain injury is not known and was investigated in a pig model of global cerebral ...
eLife11d
BCAS2 promotes primitive hematopoiesis by sequestering β-catenin within the nucleus
However, whether BCAS2 has other functions within the nucleus remains largely unknown. Here, we show that BCAS2 is essential for primitive hematopoiesis in zebrafish and mouse embryos. The activation ...
eLife13d
Intergenerational transport of double-stranded RNA limits heritable epigenetic changes
Department of Cell Biology and Molecular Genetics, University of Maryland, College Park, MD 20742, USA In this report, the authors present valuable findings identifying a novel worm-specific protein ...